Replacing a player like Pig Brown will not be easy, but someone in the secondary must pick up where Brown left off. Free safety William Moore will now be expected to make even more contributions on the defense. Also, Justin Garrett and Del Howard will be seeing more action and need to take advantage of the opportunity.

2. Buffs Defense Plays Tough At Home

Colorado's defense has given up an average of 14.8 point per game at home this season. Florida State scored 16 points, Oklahoma scored 24 points, even Kansas' high scoring offense could only manage 19 points last week in Boulder. The Tigers have played any low-scoring games this season and probably don't want to. Chase Daniel and the Missouri offense will need to find many creative ways to move the football which shouldn't be a problem.

3. Keep An Eye Out For Ralphie

Ralphie can be an imposing force when he hits Folsom Field. He has the quickness of Marshall Faulk, the shiftiness of Barry Sanders, and the power of Earl Campbell...a rare combination of talent. The Tigers need to avoid this guy at all cost in order to have a chance in this game. Otherwise, Missouri's injury list might get a little longer.

PREDICTION - Missouri 38, Colorado 23

The Tigers have not had much success in Boulder the past 24 years, winning there only once. But the Tigers once again The Buffs did upset Oklahoma at Folsom Field earlier this season, I don't see a similar event happening against the boys from Ol' Mizzou.